
Updated: April 13, 2026
Vedema, a Luxury Collection Resort offers upscale accommodations with a high-end restaurant, spa, poolside bar, and complimentary breakfast.
Indulge in ultimate Mediterranean luxury at this prestigious Luxury Collection resort in enchanting Megalochori, where 18th-century village charm meets world-class sophistication across 9 acres of lush gardens and courtyards. You’ll discover a sanctuary of tranquility featuring elegant suites and villas scattered throughout meticulously restored traditional buildings, each showcasing authentic Cycladic architecture with modern luxury amenities.

The resort’s crown jewel infinity pool creates a spectacular aquatic theater with unobstructed Aegean Sea views, while multiple dining venues celebrate Greek cuisine with contemporary flair using ingredients from the property’s own organic garden. Selene Restaurant, helmed by renowned Chef Ettore Botrini, offers Michelin-starred dining experiences that elevate your stay to extraordinary heights.

Wake each morning to a champagne breakfast service on your private terrace, then explore the resort’s wine cave featuring rare Santorini vintages, or unwind at the award-winning spa with treatments inspired by ancient Greek wellness traditions. With its perfect blend of authentic island heritage, sophisticated luxury, and personalized service, Vedema provides an exclusive retreat for discerning travelers seeking the ultimate expression of refined Greek hospitality in one of Santorini’s most beautiful and historically significant locations.
Create a custom itinerary including this hotel, restaurants, and attractions. Perfect for planning your ideal Santorini experience.
Create Itinerary15th-century winery setting in Megalochori, Selene restaurant by chef Ettore Botrini, rare-vintage wine cave, two outdoor pools, full-service spa, suites and villas with private pools, Marriott Luxury Collection service
Families, couples, luxury village stays
Vedema, a Luxury Collection Resort in the medieval village of Megalohori is a 5 star sanctuary converted from a 15th‑century winery. The resort offers 74 spacious suites and villas with private terraces—many with jacuzzis or private pools—two outdoor pools, a full‑service spa, sauna, steam room, fitness center and wine‑tasting. Guests enjoy multiple restaurants and bars, complimentary breakfast, free Wi Fi and parking, a private beach and personalized service. Check‑in 3:00 PM, check‑out 11:00 AM.
4.6 out of 5
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* Prices may vary based on dates and room types
* We recommend booking early for peak season
Address
Megalochori 847 00, Greece
Santorini, Greece
Phone
Interactive map showing the location of Vedema, a Luxury Collection Resort, Santorini in Santorini, Greece
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Prime Location
Situated in one of the most desirable areas of the island.
Accessibility
Easy access to public transportation and major attractions.
Nearby Amenities
Walking distance to highly-rated restaurants and shops.